One of the molecules found in raspberries is raspberry ketone. Credit: Raspberries photo via Shutterstock View full size image

A raspberry contains 200 molecules that contribute to its distinct raspberry flavor. One of those, raspberry ketone, was singled out by food manufacturers decades ago for its potent smell. Berry flavored candy, soaps and candles made today likely use raspberry ketone. Recently the raspberry ketone garnered public attention again, but this time as a purported weight loss aid.

Around 2010, scientists noticed that raspberry ketone had a similar molecular structure to capsaicin, which is the chemical responsible forthe heat in chili peppers. Preliminary studies also suggested that capsaicin prevents weight gain. In light of these findings, scientists ran studies in mice and on human tissue to see if raspberry ketone also influences weight gain.

Does raspberry ketone work?

… preliminary studies have been done to look at raspberry ketone as a weight loss aid, and none of these were done in humans. But the studies on mice or cells have signaled a potential weight loss effect. A 2005 study on mice fed a high-fat diet found raspberry ketone prevented weight gain in the liver, and gains of visceral fat (“belly fat”) that surrounds organs, according to the paper in the journal Life Sciences.

Another study showed raspberry ketone increased the breakdown of lipids (fat molecules) within fat cells. The 2010 paper in the journal Planta Medica also found raspberry ketone spurred fat cells to secrete more of the protein adiponectin. Low levels of adiponectin in the body are more common among  people who are obese, and those with type 2 diabetes.

Preliminary research has also found that raspberry ketone – when applied directly on the skin – could help combat signs of aging. A 2008 study of 15 people found applications of raspberry ketone improved both skin elasticity and hair growth over five months, according to the study in the journal Growth Hormone & IGF Research.

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